Publications

Recent Publications

Updated 19/08/2018

Dual Roles for Potassium Hydride in Haloarene Reduction: CSNAr and SET Reduction via Organic Electron Donors Formed in Benzene
Barham, J. P.; Dalton, S. E.; Allison, M.; Nocera, G.; Young, A.; John, M. P.; McGuire, T. M.; Campos, S.; Tuttle, T.; Murphy, J. A., J. Am. Chem. Soc., 2018

Applications of organocatalysed visible-light photoredox reactions for medicinal chemistry
Bogdos, M. K.; Pinard, E.; Murphy, J. A., Beilstein J. Org. Chem., 2018

Electron Transfer reactions: KOtBu (but not NaOtBu) Photo-reduces Benzophenone, under Activation by Visible Light
Nocera, G.; Young, A.; Palumbo, F.; Emery, K. J.; Coulthard, G.; McGuire, T. M.; Tuttle, T.; Murphy, J. A., J. Am. Chem. Soc., 2018

KOtBu as a single electron donor? Revisiting the halogenation of alkanes with CBr4 and CCl4
Emery, K. J.; Young, A.; Arokianathar, J. N.; Tuttle, T.; Murphy, J. A., Molecules, 2018

Reduction of nitroarenes, azoarenes and hydrazine derivatives by an organic electron donor
Cumine, F.; Palumbo, F.; Murphy, J. A., Tetrahedron, 2018

Selectively targeting the kinome-conserved lysine of PI3Kdelta as a general approach to covalent kinase inhibition
Dalton, S. E.; Dittus, L.; Thomas, D. A.; Convery, M. A.; Nunes, J.; Bush, J. T.; Evans, J. P.; Werner, T.; Bantscheff, M.; Murphy, J. A.; Campos, S., J. Am. Chem. Soc., 2018

A computational study of anionic alkoxide-allene and amide-allene cyclizations
Cumine, F.; Young, A.; Reissig, H.-U.; Tuttle, T.; Murphy, J. A., Eur. J. Org. Chem., 2017

Evidence of single electron transfer from the enolate anion of an N,N'-dialkyldiketopiperazine additive in BHAS coupling reactions
Emery, K. J.; Tuttle, T.; Murphy, J. A., Org. Biomol. Chem., 2017

Electron Transfer and Hydride Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu-Et3SiH)
Smith, A. J.; Young, A.; Rohrbach, S.; O'Connor, E. F.; Allison, M.; Wang, H.-S.; Poole, D. L.; Tuttle, T.; Murphy, J. A., Angew. Chem. Int. Ed., 2017

A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene-arene coupling
Cumine, F.; Zhou, S.; Tuttle, T.; Murphy, J. A., Org. Biomol. Chem., 2017

Effect of solvent on radical cyclisation pathways: SRN1 vs. aryl-aryl bond forming mechanisms
Emery, K. J.; Murphy, J. A.; Tuttle, T., Org. Biomol. Chem., 2017

Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C–H Functionalization of Trialkylamine N-CH3 Groups
Barham, J. P.; John, M. P.; Murphy, J. A., J. Am. Chem. Soc., 2016

C-C Bond-Forming Reactions of Ground-State Aryl Halides Under Reductive Activation
Emery, K. J.; Tuttle, T.; Kennedy, A. R.; Murphy, J. A., Tetrahedron, 2016

KOtBu: a Privileged Reagent for Electron Transfer Reactions?
Barham, J. P.; Coulthard, G.; Emery, K. J.; Doni, E.; Cumine, F.; Nocera, G.; John, M. P.; Berlouis, L. E. A.; McGuire, T. M.; Tuttle, T.; Murphy, J. A., J. Am. Chem. Soc., 2016

Proton Transfer Reactions of a Bridged Bis-Propyl Bis-Imidazolium Salt
Massey, R. S.; Quinn, P.; Zhou, S.; Murphy, J. A.; O'Donoghue, A. C., J. Phys. Org. Chem., 2016

Double Deprotonation of Pyridinols Generates Potent Organic Electron-Donor Initiators for Haloarene-Arene Coupling
Barham, J. P.; Coulthard, G.; Kane, R. G.; Delgado, N.; John, M. P.; Murphy, J. A., Angew. Chem. Int. Ed., 2016

Predicting the Reducing Power of Organic Super Electron Donors
Anderson, G. M.; Cameron, I.; Murphy, J. A.; Tuttle, T., RSC Adv., 2016

Pushing the Limits of Neutral Organic Electron Donors: A Tetra(iminophosphorano)-Substituted Bispyridinylidene
Hanson, S. S.; Doni, E.; Traboulsee, K. T.; Coulthard, G.; Murphy, J. A.; Dyker, C. A., Angew. Chem. Int. Ed., 2015

Electron Transfer-Induced Coupling of Haloarenes to Styrenes and 1,1-Diphenylethenes Triggered by Diketopiperazines and Potassium tert-Butoxide
Doni, E.; Zhou, S.; Murphy, J. A., Molecules, 2015

"The Third Hydrogenase" Chap. 5 in "Bioinspired Catalysis: Metal-Sulfur Complexes" W. Weigand, P. Schollhammer (Editors) ISBN: 978-3-527-33308-0, 440 pages, October 2014, Wiley.
Scullion, C.; Murphy, J. A.

One-pot Functionalisation of N-substituted Tetrahydroisoquinolines by Photooxidation and Tunable Organometallic Trapping of Iminium Intermediate
Barham, J. P.; John, M. P.; Murphy, J. A., Beilstein J. Org. Chem., 2014

Reductive Decyanation of Malononitriles and Cyanoacetates using Photoactivated Neutral Organic Super-Electron-Donors
Doni, E.; Murphy, J. A., Org. Chem. Front., 2014

Identifying the Roles of Amino Acids, Alcohols and 1,2-Diamines as Mediators in Coupling of Haloarenes to Arenes
Zhou, S.; Doni, E.; Anderson, G. M.; Kane, R. G.; MacDougall, S. W.; Ironmonger, V. M.; Tuttle, T.; Murphy, J. A., J. Am. Chem. Soc., 2014

Discovery and Development of Organic Super-Electron-Donors
Murphy, J. A., J. Org. Chem., 2014

Evolution of Neutral Organic Super-Electron-Donors and their Applications
Doni, E.; Murphy, J. A., Chem. Commun., 2014

Organic Super-Electron-Donors: Initiators in Transition Metal-Free Haloarene-Arene Coupling
Zhou, S.; Anderson, G. M.; Mondal, B.; Doni, E.; Ironmonger, V.; Kranz, M.; Tuttle, T.; Murphy, J. A., Chem. Sci., 2014

Metal-Free Reductive Cleavage of C-N and S-N Bonds by Photoactivated Electron Transfer from a Neutral Organic Donor
O'Sullivan, S.; Doni, E.; Tuttle, T.; Murphy, J. A., Angew. Chem. Int. Ed., 2014

For a full list of our publications to date, click here